14 avril 2015 ~ 0 Commentaire

Preventative trial in arthritis to bring hope for millions, UK

A pioneering drug to be tested could bring hope to the millions of Britons who are likely to one day suffer from arthritis. The drug aims to prevent people from developing arthritis, unlike existing treatments that treat the debilitating disease once it has set in.

Led by researchers from England’s National Institute for Health Research (NIHR), the study of the drug Abatacept will be the world’s largest ever trial investigating whether targeted immunotherapy can prevent rheumatoid arthritis in individuals considered to be at high risk of developing the disease. The study has been made possible by the NIHR Translational Research Partnership bringing together 31 of the country’s leading hospitals and universities to take part in the trial.

Professor Dame Sally C Davies FRS FMedSci, Chief Medical Officer for England said: « Preventing chronic diseases and finding ways to minimise their progression is vital for patients’ quality of life. I am delighted that the NIHR is working with Bristol-Myers Squibb on this important preventative study. The Government created Translational Research Partnerships to work in collaboration with the life sciences industry specifically to drive the development of new treatment options for people with debilitating conditions such as rheumatoid arthritis. »

Mark Samuels from the NIHR said: « This trial takes us a real step closer to being able to prevent arthritis. I’m delighted that the NIHR is leading such an exciting study. The NIHR is perfectly placed to lead such a big trial in experimental medicine. The study offers hope that this debilitating condition can be prevented. »

Rheumatoid arthritis currently affects more than 500,000 people in the UK – causing great pain and, in some cases, disability. The cost to the NHS is

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